"Do not listen to anyone, we are going to go to a referendum", Masoud Barzani said during a campaign for the Kurdish referendum in Duhok Province.
Parliament reconvened in Erbil, the seat of the Kurdistan Regional Government (KRG) in northern Iraq, where an overwhelming majority of the Kurdish lawmakers taking part backed the plan.
The US and other Western powers have expressed opposition to Kurdistan's independence vote, fearing it will fuel regional unrest and distract attention from ongoing campaigns to rout Islamic State in Iraq and Syria.
The White House issued a statement following the Kurdish vote, calling on the Kurds to call off the vote and "enter into serious and sustained dialogue with Baghdad".
Controversially, the vote will also be held in so-called disputed areas outside the Kurdistan Regional Government's (KRG) official boundaries.
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Iraq's parliament voted on Thursday to sack the governor of oil-rich Kirkuk over his decision for the northern province to vote in a Kurdish independence referendum opposed by Baghdad.
"We still haven't heard a proposal that can be an alternative to the Kurdistan referendum", he said.
Sixty-five members of parliament voted in favour of holding the referendum for the Kurdistan region.
Ankara, which has warned the referendum would come at a "cost", has close economic and political relations with the KRG and Barzani.
Under this plan, a well-placed source told AFP, the global community will oversee negotiations on revenue sharing in Iraq's oil budget and payment for Kurdish militia fighters.
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The planned vote has escalated tensions with Baghdad as well as neighboring Turkey and Iran - countries home to sizeable Kurdish populations.
Opposition parties Goran and Jamaa Islamiya earlier said they would boycott the session.
There is widespread support among Iraqi Kurds for an independent state.
The Kurdish region won autonomy in 2005 under a constitution that established a federal republic in Iraq.
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