City is on a maximum of nine points and should need to win only one of its last three games to qualify for the knockout stage.
De Bruyne was the key in killing the game early, crossing for Gabriel Jesus to score City's second inside 13 minutes.
"Today we won against an incredible team".
Policeman gunned down in Quetta shortly after blast
On August 13 this year, at least 15 people, including eight soldiers, were martyred when a military truck was targeted in Quetta . Pakistani leaders, including Imran Khan, and members of the civil society condemned the attack, praying for the victims.
Before the game Guardiola had lavished praise on Maurizio Sarri's Napoli, who are top of Serie A with eight wins from eight games, and afterwards he made the surprising claim they were the best opponent he had ever faced. "It's one of the wins I'm most proud of in my whole career".
"I am going to show Napoli to my players - how good they are".
De Koster added: "He can't expect to win the Ballon d'Or at the moment, he's still far from footballers like Messi and CR7".
"I've seen a huge step forward compared with the match in Real Madrid a year ago when we were lucky enough to score first".
Oil steady as U.S. output gains offset Middle East tensions
During the previous round of sanctions against Iran, about 1 million bbl/dd of oil was cut from global markets. Analysts forecast US crude inventories declined by about 4.2 million barrels in the week to October 13.
Belgian midfielder De Bruyne fired a long-range shot against the bar in the 25th after a swift City counter-attack and then Jesus had a goalbound effort cleared off the line by Kalidou Koulibaly.
Both sides have been in devastating form in front of goal, scoring 71 goals between them this season.
At least six dead after building crumbles downs in Bengaluru's Ejipura
However, the Karnataka Home Minister has negated the assumption of cylinder blast behind the building collapse. He added that five of these were residents of the building itself, while one of the deceased was a neighbour.
"We had a little discussion at the time, it happens", he said.